Diseases & ConditionsCushing’s Disease |
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What is Cushing’s disease?
Cushing’s disease is due to an overproduction of cortisol, a steroid normally produced by your dog’s adrenal glands. Cushing's disease is also called hyperadrenocorticism. What will Cushing’s disease look like in my dog?
Typical symptoms include increased thirst and hunger, increased urination, panting, the development of a pot-belly, hair loss, skin infections, muscle loss and weakness. Cushing’s disease generally occurs in middle-aged to senior dogs. Although any breed or mix can get Cushing’s disease, it occurs more frequently in certain breeds such as Boston Terriers, Boxers and Dachshunds. How does my dog get Cushing’s disease?
Your dog can get Cushing’s disease in essentially three ways. First, it may be caused by over-secretion of a hormone called ACTH. The pituitary gland in your dog’s brain will cause the ACTH over-secretion which, in turn, will trigger the adrenal glands to over-secrete cortisol. Second, this disease may be caused by either a cortisol-secreting benign or malignant tumor. This is much less common than the pituitary-dependent cause. Third, Cushing’s disease may have an iatrogenic cause. Iatrogenic essentially means that it was caused by accident due to medical intervention. In this case, the iatrogenic cause is due to the over-administration of steroids to your dog. How is Cushing’s disease diagnosed?
Your vet will generally use a combination of diagnostic procedures to diagnose Cushing’s disease. Your dog’s symptoms, routine blood work and urine analysis will provide a basis for suspicion that your dog has Cushing’s disease. Your vet will also want to know if your dog has been prescribed any steroids. An ACTH stimulation test can confirm cortisol over-secretion. Imaging techniques such as X-rays and an ultrasound can be used to search for adrenal gland tumors. How is Cushing’s disease treated?
Usually, treatment consists of putting your dog on medication to reduce the amount of cortisol secretion by the adrenal glands. If Cushing’s disease has been caused by an adrenal gland tumor, the tumor may be surgically removed. If Cushing’s disease has been caused by your dog’s steroid use, reducing or stopping the steroids will help reduce symptoms. How is Cushing’s disease prevented?
The only means of prevention applies to iatrogenic Cushing’s disease, which can be prevented by giving your dog steroids only when absolutely necessary and in very carefully controlled levels. Can I get Cushing’s disease from my dog?
No, you cannot get this condition from your dog. |
















